Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.57 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296954 | 0.84 | GPR119 (0.63) | GPR119PDE2APDE3BPDE3A | |
| SCHEMBL9686758 | 0.83 | PDE2A (0.62) | GPR119PDE2APDE3BPDE3A | |
| SCHEMBL7303015 | 0.82 | PDE3B (0.62) | GPR119PDE3BPDE3A | |
| SCHEMBL9686551 | 0.80 | GPR119 (0.56) | GPR119PDE2APDE3BPDE3A | |
| SCHEMBL7328135 | 0.79 | PDE3B (0.55) | GPR119PDE2APDE3BPDE3A | |
| SCHEMBL7296587 | 0.78 | GPR119 (0.57) | GPR119PDE3BPDE3A | |
| SCHEMBL9781549 | 0.78 | GPR119 (0.55) | GPR119PDE2APDE3BPDE3A | |
| SCHEMBL9687779 | 0.77 | GPR119 (0.51) | GPR119PDE2APDE3BPDE3A | |
| SCHEMBL6934156 | 0.76 | GPR119 (0.74) | GPR119PDE2APDE3BPDE3A | |
| SCHEMBL9686555 | 0.76 | GPR119 (0.60) | GPR119PDE2APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |