Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | ALB | P02768 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296072 | 0.86 | BCHE (0.45) | BCHEALBACHEMCHR1 | |
| SCHEMBL1268 | 0.83 | BCHE (0.62) | BCHEALBACHEBRD4 | |
| SCHEMBL7286323 | 0.76 | BRD4 (0.47) | BCHEALBACHEBRD4 | |
| SCHEMBL7291967 | 0.73 | CYP1A2 (0.56) | — | |
| SCHEMBL7285339 | 0.72 | BRD4 (0.42) | BCHEALBACHEBRD4MCHR1 | |
| SCHEMBL7292567 | 0.71 | MCHR1 (0.52) | BCHEALBACHEBRD4MCHR1 | |
| SCHEMBL7291788 | 0.69 | RIPK3 (0.42) | BCHEALBACHEBRD4 | |
| SCHEMBL588 | 0.69 | BCHE (0.69) | BCHEALBACHEBRD4 | |
| SCHEMBL6921111 | 0.68 | CSNK2A2 (0.53) | BRD4 | |
| SCHEMBL7294032 | 0.67 | BCHE (0.49) | BCHEALBACHEMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353983-B1 | Lactam derivatives | GLAXO GROUP LTD (GB) | 1996-05-29 | — | — | EP | disclosed |
| US-5183820-A | Useful for treatment of nausea, vomiting, irritable bowel syndrome and dyspepsia | GLAXO GROUP LIMITED (GB) | 1993-02-02 | — | — | US | disclosed |