Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341887 | 0.88 | GAA (0.48) | KDM4ERAB9AALDH1A1LMNAHTT | |
| SCHEMBL4707952 | 0.85 | MAPT (0.59) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL7289360 | 0.83 | LCK (0.49) | KDM4ERAB9AALDH1A1LMNAHTT | |
| SCHEMBL7289640 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL2394192 | 0.81 | POLB (0.60) | KDM4ERAB9AALDH1A1LMNAHTT | |
| SCHEMBL5490882 | 0.81 | MAPT (0.59) | KDM4ERAB9AALDH1A1LMNAHTT | |
| SCHEMBL2605631 | 0.81 | KDM4E (0.71) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL7807601 | 0.81 | CYP1A2 (0.68) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL7292664 | 0.81 | CYP1A1 (0.43) | KDM4ERAB9AALDH1A1HTTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7808111 | 0.79 | CYP1A2 (0.66) | KDM4EALDH1A1LMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848000-B1 | Pharmaceutical pyridine derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5965730-A | SELECTIVE PHOSPHODIESTEARASE IV INHIBITOR HAVING BRONCHODIALATION AND ANTI-INFLAMMATORY ACTIVITY; PROPHYLAXIS AND TREATMENT OF ASTHMA | TANABE SEIYAKU CO., LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0848000-A1 | Pharmaceutical pyridine derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |