Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7808111 | 0.98 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL31331742 | 0.87 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL5685571 | 0.87 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL4707952 | 0.85 | MAPT (0.59) | CYP1A2CYP3A4CYP2C19ALDH1A1HTT | |
| SCHEMBL12682379 | 0.84 | CYP3A4 (0.75) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL5490882 | 0.84 | MAPT (0.59) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL2394192 | 0.84 | POLB (0.60) | ALDH1A1HTTLMNAL3MBTL1KDM4E | |
| SCHEMBL2605631 | 0.84 | KDM4E (0.71) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL212051 | 0.83 | TUBB4A (0.60) | TSHRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL8132043 | 0.83 | KDM4E (0.57) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000050381-A1 | METHOD FOR PREPARING 2-AMINOBENZOPHENONE DERIVATIVES | RHODIA CHIMIE (FR) | 2000-08-31 | — | — | WO | claimed |
| US-6011178-A | Process for the preparation of 2-amino-4,5,3',4'-tetramethoxybenzophenone | LONZA, LTD. (CH) | 2000-01-04 | — | — | US | claimed |
| EP-0941987-A1 | Process for the preparation of 2-Amino-4,5,3',4'-tetramethoxybenzophenone | LONZA A.G. (CH) | 1999-09-15 | — | — | EP | claimed |
| JP-11310558-A | — | — | None | — | — | JP | disclosed |
| JP-11310558-A | — | — | None | — | — | JP | disclosed |
| EP-0686630-B1 | Quinoline derivatives and pharmaceutical composition containing them | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-0608870-B1 | Quinoline or quinazoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000050381-A1 | METHOD FOR PREPARING 2-AMINOBENZOPHENONE DERIVATIVES | RHODIA CHIMIE (FR) | 2000-08-31 | — | — | WO | disclosed |
| EP-0634169-B1 | Quinoline or quinazoline derivatives and their use in the manufacture of a medicament for the treatment of osteoporosis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-01-05 | — | — | EP | disclosed |
| US-6011178-A | Process for the preparation of 2-amino-4,5,3',4'-tetramethoxybenzophenone | LONZA, LTD. (CH) | 2000-01-04 | — | — | US | disclosed |
| US-6011178-A | Process for the preparation of 2-amino-4,5,3',4'-tetramethoxybenzophenone | LONZA, LTD. (CH) | 2000-01-04 | — | — | US | disclosed |
| EP-0766681-A1 | PROCESSES FOR PRODUCTION OF QUINOLINE OR QUINAZOLINE DERIVATIVES AND INTERMEDIATES THEREFOR | Takeda Chemical Industries, Ltd. (JP) | 1997-04-09 | — | — | EP | disclosed |
| EP-0749426-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS, IN PARTICULAR FOR TREATING ARTHRITIS | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996000223-A1 | PROCESSES FOR PRODUCTION OF QUINOLINE OR QUINAZOLINE DERIVATIVES AND INTERMEDIATES THEREFOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-04 | — | — | WO | disclosed |
| EP-0686630-A1 | Quinoline derivatives and pharmaceutical composition containing them | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-13 | — | — | EP | disclosed |
| WO-1995024394-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS, IN PARTICULAR FOR TREATING ARTHRITIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |
| US-5436247-A | Antiinflammatory agents or antiarthritic agents | TAKEDA CHEMICAL INDUSTRIES (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0634169-A1 | Pharmaceutical composition containing quinoline or quinazoline derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0608870-A1 | Quinoline or quinazoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0567107-A1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |