Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 5/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.38 |
| ▸ | IL1RN | P18510 | 4/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294519 | 0.91 | GRB2 (0.46) | GRB2PPIDLCKLNPEP | |
| SCHEMBL27406640 | 0.89 | GRB2 (0.47) | GRB2NPY1RNPY4R | |
| SCHEMBL7296838 | 0.87 | PPID (0.41) | PPIDERAP2IL1RNERAP1NPY1R | |
| SCHEMBL11856676 | 0.86 | LCK (0.49) | PPIDERAP2IL1RNERAP1NPY1R | |
| SCHEMBL7302573 | 0.84 | MAPT (0.42) | GRB2LCKLNPEP | |
| SCHEMBL9777172 | 0.82 | CAPN1 (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL7425286 | 0.82 | CAPN1 (0.51) | — | |
| SCHEMBL7295205 | 0.81 | ALOX15 (0.43) | GRB2LCK | |
| SCHEMBL1068720 | 0.80 | PPID (0.42) | GRB2PPIDERAP2IL1RNNPY1R | |
| SCHEMBL25193395 | 0.79 | GRB2 (0.46) | GRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393781-B1 | Dopamine pro-drug | ZAMBON SPA (IT) | 1995-02-08 | — | — | EP | disclosed |
| US-5073547-A | DOPAMINE PRO-DRUG | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1991-12-17 | — | — | US | disclosed |
| EP-0393781-A2 | Dopamine pro-drug | ZAMBON GROUP S.p.A. (IT) | 1990-10-24 | — | — | EP | disclosed |