Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | TPH1 | P17752 | 9/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267192 | 0.80 | SLC7A5 (0.53) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL31267197 | 0.80 | SLC7A5 (0.53) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL156189 | 0.77 | SLC7A5 (0.74) | CYP1A2SLC7A5MAPTLMNAMEN1 | |
| SCHEMBL837014 | 0.77 | SLC7A5 (0.74) | CYP1A2SLC7A5MAPTLMNAMEN1 | |
| SCHEMBL31370206 | 0.75 | SLC7A5 (0.54) | CYP1A2SLC7A5MAPTLMNAMEN1 | |
| SCHEMBL2310526 | 0.74 | SLC7A5 (0.83) | CYP1A2SLC7A5MAPTLMNAMEN1 | |
| SCHEMBL3452908 | 0.74 | LMNA (0.80) | CYP1A2MAPTLMNAMEN1KMT2A | |
| SCHEMBL7298379 | 0.74 | MAPT (0.55) | CYP1A2MAPTLMNAMEN1KMT2A | |
| SCHEMBL11725137 | 0.73 | SLC7A5 (0.51) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL11725124 | 0.73 | SLC7A5 (0.51) | CYP1A2SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |