Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297429 | 0.73 | KMT2A (0.39) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7350391 | 0.70 | KMT2A (0.39) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL28198306 | 0.69 | SMN1; SMN2 (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL3868248 | 0.67 | GAA (0.35) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL464563 | 0.65 | KCNH2 (0.43) | KMT2AALDH1A1POLBMAPTFDPS | |
| SCHEMBL8541839 | 0.64 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL2283802 | 0.64 | — | — | |
| SCHEMBL20518770 | 0.64 | — | — | |
| SCHEMBL19262387 | 0.63 | — | — | |
| SCHEMBL19386625 | 0.62 | EHMT2 (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |