Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290309 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTHPGDNPC1 | |
| SCHEMBL8578287 | 0.71 | NPC1 (0.38) | ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL8578786 | 0.70 | KDM4E (0.61) | ALDH1A1LMNAMAPTNPC1HTT | |
| SCHEMBL8607073 | 0.69 | KDM4E (0.49) | ALDH1A1LMNAMAPTNPC1MAPK1 | |
| SCHEMBL7299533 | 0.68 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTHPGDNPC1 | |
| SCHEMBL8122081 | 0.68 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTNPC1MAPK1 | |
| SCHEMBL8124327 | 0.68 | KDM4E (0.40) | ALDH1A1MAPTHPGDNPC1MAPK1 | |
| SCHEMBL8123737 | 0.68 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTNPC1MAPK1 | |
| SCHEMBL8127824 | 0.66 | KCNH2 (0.39) | ALDH1A1LMNAMAPTNPC1MAPK1 | |
| SCHEMBL8124724 | 0.65 | KDM4E (0.38) | ALDH1A1LMNAMAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426018-A2 | Thiophene compounds and their pharmaceutical uses | YOSHITIOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |