Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584121 | 0.80 | MAPT (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL3195006 | 0.76 | TSHR (0.32) | POLB | |
| SCHEMBL9585546 | 0.76 | FABP6 (0.41) | NPC1RAB9AMAOBMAPTKDM4E | |
| SCHEMBL2350606 | 0.76 | MAPT (0.50) | AHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7289615 | 0.72 | CA12 (0.41) | NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL7297786 | 0.72 | MAPT (0.38) | KMT2ANPC1RAB9AMAPTKDM4E | |
| SCHEMBL21994804 | 0.72 | — | — | |
| SCHEMBL9586825 | 0.72 | MTNR1A (0.42) | NPC1RAB9AMAOBMAPTKDM4E | |
| SCHEMBL1492678 | 0.72 | PARP1 (0.41) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL3072209 | 0.72 | MAOB (0.56) | AHRMAP3K14MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |