Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375274 | 0.82 | AHR (0.42) | MEN1KMT2AALDH1A1RXFP1KDM4E | |
| SCHEMBL18242843 | 0.78 | MEN1 (0.46) | MEN1KMT2AALDH1A1RXFP1KDM4E | |
| SCHEMBL8723829 | 0.75 | CYP2A6 (0.37) | MEN1KMT2AALDH1A1RXFP1KDM4E | |
| SCHEMBL5255668 | 0.75 | AHR (0.37) | MEN1KMT2AALDH1A1RXFP1KDM4E | |
| SCHEMBL5255665 | 0.75 | CYP2A6 (0.37) | MEN1KMT2AALDH1A1RXFP1KDM4E | |
| SCHEMBL8723827 | 0.75 | CYP2A6 (0.37) | MEN1KMT2AALDH1A1RXFP1KDM4E | |
| SCHEMBL29344202 | 0.75 | CYP2A6 (0.37) | MEN1KMT2AALDH1A1RXFP1KDM4E | |
| SCHEMBL2362910 | 0.72 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL15351928 | 0.70 | CYP2A6 (0.44) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL29620230 | 0.69 | TSHR (0.53) | MEN1KMT2AALDH1A1RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |