Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.31 |
| ▸ | GBA1 | P04062 | 2/20 | 0.30 |
| ▸ | UGCG | Q16739 | 2/20 | 0.30 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129491 | 0.95 | — | — | |
| SCHEMBL6305480 | 0.88 | SPHK1 (0.38) | NAAASPHK2SPHK1GBA1UGCG | |
| SCHEMBL126364 | 0.85 | — | — | |
| SCHEMBL131976 | 0.84 | SPHK1 (0.35) | SPHK2SPHK1GBA1UGCGGBA2 | |
| SCHEMBL7303667 | 0.84 | SPHK2 (0.35) | NAAASPHK2SPHK1GBA1UGCG | |
| SCHEMBL126800 | 0.82 | TSHR (0.38) | SPHK2SPHK1GBA1UGCGGBA2 | |
| SCHEMBL131035 | 0.80 | SPHK1 (0.40) | SPHK2SPHK1GBA1UGCGGBA2 | |
| SCHEMBL5168 | 0.75 | — | — | |
| SCHEMBL4497381 | 0.74 | NFE2L2 (0.36) | — | |
| SCHEMBL12268104 | 0.74 | TSHR (0.34) | NAAASPHK2SPHK1GBA1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |