Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | PPIA | P62937 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935581 | 0.86 | BRD4 (0.68) | BRD4GAAKMT2AL3MBTL1TDP1 | |
| SCHEMBL13652590 | 0.86 | BRD4 (0.73) | BRD4GAAKMT2AL3MBTL1TDP1 | |
| SCHEMBL5174575 | 0.86 | BRD4 (0.68) | BRD4GAAKMT2AL3MBTL1TDP1 | |
| SCHEMBL3619403 | 0.85 | BRD4 (0.77) | BRD4GAAL3MBTL1TDP1PPIA | |
| SCHEMBL4297414 | 0.84 | BRD4 (0.74) | BRD4GAAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6169172 | 0.83 | MEN1 (0.83) | GAAKMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL8924076 | 0.83 | BRD4 (1.00) | BRD4KMT2AL3MBTL1TDP1MEN1 | |
| SCHEMBL18051152 | 0.81 | BRD4 (0.66) | BRD4GAAKMT2AL3MBTL1TDP1 | |
| SCHEMBL11549645 | 0.81 | BRD4 (0.70) | BRD4GAAKMT2AL3MBTL1TDP1 | |
| SCHEMBL38660185 | 0.81 | BRD4 (0.70) | BRD4GAAKMT2AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0453658-A2 | Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-10-30 | — | — | EP | disclosed |