Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | PPIA | P62937 | 5/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619403 | 0.88 | BRD4 (0.77) | BRD4TDP1L3MBTL1PPIASGMS2 | |
| SCHEMBL5174575 | 0.86 | BRD4 (0.68) | BRD4TDP1L3MBTL1PPIASGMS2 | |
| SCHEMBL8924076 | 0.85 | BRD4 (1.00) | BRD4TDP1L3MBTL1PPIARAB9A | |
| SCHEMBL18586598 | 0.85 | BRD4 (0.63) | BRD4TDP1L3MBTL1PPIASGMS2 | |
| SCHEMBL8366817 | 0.85 | BRD4 (0.59) | BRD4HTTNPC1CASP3RAB9A | |
| SCHEMBL5148514 | 0.85 | BRD4 (0.63) | BRD4TDP1L3MBTL1PPIASGMS2 | |
| SCHEMBL7298832 | 0.84 | BRD4 (0.70) | BRD4TDP1L3MBTL1PPIASGMS2 | |
| SCHEMBL11549645 | 0.84 | BRD4 (0.70) | BRD4TDP1L3MBTL1PPIASGMS2 | |
| SCHEMBL38660185 | 0.84 | BRD4 (0.70) | BRD4TDP1L3MBTL1PPIASGMS2 | |
| SCHEMBL10425907 | 0.84 | BRD4 (0.54) | BRD4TDP1L3MBTL1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010180-A2 | IL-8 RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007124423-A2 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-01 | — | — | WO | claimed |
| EP-0235878-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1987-09-09 | — | — | EP | claimed |
| CN-1391473-A | VLA-4 inhibitor compounds | DAIICHI SEIYAKU CO (JP) | 2003-01-15 | — | — | CN | disclosed |
| EP-0967875-B1 | SYNERGISTIC JUVENOID/CHITIN SYNTHESIS INHIBITOR TERMITICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2002-01-23 | — | — | EP | disclosed |
| US-6093415-A | CONTROLLING TERMITES COMPRISING A JUVENILE HORMONE MIMIC | DOW AGROSCIENCES LLC (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0967875-A1 | SYNERGISTIC JUVENOID/CHITIN SYNTHESIS INHIBITOR TERMITICIDE COMPOSITIONS | Dow AgroSciences LLC (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998034481-A1 | SYNERGISTIC JUVENOID/CHITIN SYNTHESIS INHIBITOR TERMITICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 1998-08-13 | — | — | WO | disclosed |
| US-5698591-A | Trifluoromethanesulfinanilide, process for preparing trifluoromethanesulfonanilide from the same, and a controlling agent formulated from trifluoromethanesulfinanilide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| US-4959092-A | Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1990-09-25 | — | — | US | disclosed |
| EP-0293839-A2 | Substituted phenyl (or pyridyl) urea compound and herbicidal composition containing the same as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1988-12-07 | — | — | EP | disclosed |
| US-4490165-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds, methods for preparing same and herbicidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4308213-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4294986-A | Novel para-phenylalkoxy phenylurea and thiourea compounds and herbicidal use thereof | AMERICAN CYANAMID CO. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4289903-A | PREEMERGENCE AND POSTEMERGENCE | AMERICAN CYANAMID COMPANY (US) | 1981-09-15 | — | — | US | disclosed |