Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29964099 | 1.00 | NOS3 (0.53) | NOS3NOS2KDM4EALDH1A1MAOA | |
| SCHEMBL11778063 | 0.85 | NOS3 (0.50) | NOS3NOS2KDM4EALDH1A1MAOA | |
| SCHEMBL11779898 | 0.82 | NOS3 (0.47) | NOS3NOS2KDM4EALDH1A1MAOA | |
| SCHEMBL14001394 | 0.81 | NOS3 (0.53) | NOS3NOS2KDM4EALDH1A1MAOA | |
| SCHEMBL19794689 | 0.75 | CYP19A1 (0.41) | CYP19A1CYP11B2CYP11B1ADRA2A | |
| SCHEMBL15399817 | 0.75 | TDP1 (0.39) | NOS3NOS2CYP19A1CYP11B2CYP11B1 | |
| SCHEMBL2796047 | 0.75 | NOS3 (0.47) | NOS3NOS2KDM4EALDH1A1MAOA | |
| SCHEMBL3056563 | 0.73 | NOS3 (0.45) | NOS3NOS2KDM4EALDH1A1MAOA | |
| SCHEMBL29361631 | 0.71 | KDM4E (0.60) | NOS3NOS2KDM4EALDH1A1MAOA | |
| SCHEMBL7509399 | 0.71 | KDM4E (0.60) | NOS3NOS2KDM4EALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161102-B2 | Iminium salt organocatalysts, method of making, and methods of using | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2021-11-02 | — | — | US | disclosed |
| US-11161102-B2 | Iminium salt organocatalysts, method of making, and methods of using | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2021-11-02 | — | — | US | disclosed |
| US-20190344253-A1 | IMINIUM SALT ORGANOCATALYSTS, METHOD OF MAKING, AND METHODS OF USING | UNIV VIRGINIA PATENT FOUNDATION (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190344253-A1 | IMINIUM SALT ORGANOCATALYSTS, METHOD OF MAKING, AND METHODS OF USING | UNIV VIRGINIA PATENT FOUNDATION (US) | 2019-11-14 | — | — | US | disclosed |
| WO-2017223287-A1 | IMINIUM SALT ORGANOCATALYSTS, METHODS OF MAKING, AND METHODS OF USING | UNIVERSITY OF VIRGINIA (US) | 2017-12-28 | — | — | WO | disclosed |
| US-5605926-A | PROPHYLAXIS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5430151-A | Treatment of aids, pneumonia, caprine arthritis encephalitis, leukemia and immmunodeficiency | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| US-5204471-A | α-trifluoromethyl-substituted, saturated bicyclic amines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0528242-A2 | Trifluoromethyl containing pseudopeptides | BAYER AG (DE) | 1993-02-24 | — | — | EP | disclosed |
| EP-0527385-A1 | Alpha-trifluoromethyl substituted, saturated bicyclic amines and process for their preparation | BAYER AG (DE) | 1993-02-17 | — | — | EP | disclosed |