Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460912 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1TP53NPSR1CPA1 | |
| SCHEMBL2918264 | 0.74 | CHRNB2 (0.40) | — | |
| SCHEMBL25256890 | 0.74 | TP53 (0.48) | SMN1; SMN2ALDH1A1TP53NPSR1LMNA | |
| SCHEMBL29790214 | 0.74 | TP53 (0.48) | SMN1; SMN2ALDH1A1TP53NPSR1LMNA | |
| SCHEMBL29789541 | 0.73 | TP53 (0.49) | SMN1; SMN2ALDH1A1TP53NPSR1LMNA | |
| SCHEMBL27994566 | 0.72 | HDAC8 (0.30) | — | |
| SCHEMBL7598637 | 0.71 | SSTR4 (0.50) | SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL29789522 | 0.70 | TP53 (0.54) | SMN1; SMN2ALDH1A1TP53NPSR1 | |
| SCHEMBL1847750 | 0.69 | — | — | |
| SCHEMBL337230 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |