Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | GALR3 | O60755 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294721 | 0.91 | MAPT (0.61) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7292060 | 0.89 | MAPT (0.58) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7268788 | 0.88 | MAPT (0.59) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7266722 | 0.87 | MAPT (0.51) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7299102 | 0.84 | MAPT (0.48) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7273816 | 0.79 | GALR3 (0.69) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7268573 | 0.79 | MAPT (0.65) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7275977 | 0.78 | MAPT (0.62) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7267466 | 0.77 | MAPT (0.62) | MAPTGALR3SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7290853 | 0.76 | MAPT (0.45) | MAPTGALR3SMN1; SMN2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339208-B1 | 6-Oxopyridazine derivatives, process for their preparation and medicaments containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1996-02-07 | — | — | EP | disclosed |