Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40093 | 0.78 | NOS2 (0.39) | DPP4DPP8DPP9SCN9ASCN3A | |
| SCHEMBL248747 | 0.78 | NOS2 (0.39) | DPP4DPP8DPP9SCN9ASCN3A | |
| SCHEMBL248746 | 0.78 | NOS2 (0.39) | DPP4DPP8DPP9SCN9ASCN3A | |
| SCHEMBL2804278 | 0.77 | SCN9A (0.39) | DPP4DPP8DPP9SCN9ASCN3A | |
| Hydrochloric Acid SCHEMBL596114 | 0.76 | NOS2 (0.38) | DPP4DPP8DPP9SCN9ASCN3A | |
| Hydrochloric Acid SCHEMBL661789 | 0.76 | NOS2 (0.38) | DPP4DPP8DPP9SCN9ASCN3A | |
| Bromide SCHEMBL27517782 | 0.76 | NOS2 (0.38) | DPP4DPP8DPP9SCN9ASCN3A | |
| Hydrochloric Acid SCHEMBL661790 | 0.76 | NOS2 (0.38) | DPP4DPP8DPP9SCN9ASCN3A | |
| SCHEMBL7799682 | 0.75 | SCN9A (0.37) | DPP4DPP8DPP9SCN9ASCN3A | |
| SCHEMBL10608449 | 0.75 | SCN9A (0.37) | DPP4DPP8DPP9SCN9ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0228192-A2 | Renin-inhibitory oligopeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |