Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27573982 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL8217020 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL6138155 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL7304504 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL7066300 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL7075183 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL8217023 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL6808467 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL7069281 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL6808464 | 0.87 | GRIK1 (0.50) | MEN1GAAKMT2AGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575844-B1 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | HOFFMANN LA ROCHE (CH) | 1998-01-21 | — | — | EP | disclosed |
| EP-0575844-A2 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-29 | — | — | EP | disclosed |