Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 13/20 | 0.55 |
| ▸ | CTSB | P07858 | 3/20 | 0.55 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CTSH | P09668 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSC | P53634 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310611 | 0.87 | CAPN1 (0.58) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL7298531 | 0.86 | CAPN1 (0.73) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL7305468 | 0.86 | CAPN1 (0.73) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL7302942 | 0.83 | CAPN1 (0.56) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL9561659 | 0.83 | CAPN1 (0.56) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL7297672 | 0.82 | CAPN1 (0.58) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL7300862 | 0.81 | ANPEP (0.56) | CAPN1CTSBCAPN9MAPK1MMP8 | |
| SCHEMBL7298933 | 0.79 | CAPN1 (0.40) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL7305104 | 0.77 | CAPN1 (0.54) | CAPN1CTSBCAPN9MAPK1MMP8 | |
| SCHEMBL7302016 | 0.77 | CAPN1 (0.47) | CAPN1CTSBCAPN9MAPK1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | claimed |
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |