Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 8/20 | 0.53 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305104 | 0.90 | CAPN1 (0.54) | ANPEPCAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL7298531 | 0.84 | CAPN1 (0.73) | CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL7305468 | 0.84 | CAPN1 (0.73) | CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL7294898 | 0.84 | CAPN1 (0.52) | ANPEPCAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL7305128 | 0.84 | CAPN1 (0.75) | CAPN1CAPN9CTSBMAPK1MMP3 | |
| Potassium Ion SCHEMBL11209732 | 0.81 | CAPN1 (0.56) | ANPEPCAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL7299301 | 0.81 | CAPN1 (0.55) | CAPN1CAPN9CTSBMAPK1MMP3 | |
| SCHEMBL14122814 | 0.80 | CAPN1 (0.66) | CAPN1CAPN9CTSBMAPK1MMP8 | |
| SCHEMBL7310611 | 0.79 | CAPN1 (0.58) | CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL11211361 | 0.78 | CAPN1 (0.71) | ANPEPCAPN1CAPN9CTSBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | claimed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |