Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.65 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299298 | 1.00 | DPP4 (0.65) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6766614 | 0.99 | DPP4 (0.64) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6766620 | 0.99 | DPP4 (0.64) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL7289568 | 0.84 | DPP7 (0.50) | DPP4DPP7DPP8 | |
| SCHEMBL7289575 | 0.84 | DPP7 (0.50) | DPP4DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL6768024 | 0.83 | DPP7 (0.49) | DPP4DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL6768028 | 0.83 | DPP7 (0.49) | DPP4DPP7DPP8 | |
| SCHEMBL6160984 | 0.79 | DPP4 (0.85) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL6160980 | 0.79 | DPP4 (0.85) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL6160632 | 0.79 | DPP4 (0.71) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |