Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 11/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.55 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266778 | 0.89 | MAPT (0.61) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL10475494 | 0.85 | GALR3 (0.58) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL16157089 | 0.85 | MAPT (0.67) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL7266897 | 0.84 | GPR119 (0.65) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL7266508 | 0.84 | GALR3 (0.67) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL7266917 | 0.84 | GALR3 (0.66) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL7276978 | 0.83 | GALR3 (0.62) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL10472928 | 0.83 | PDE3B (0.70) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL7294835 | 0.83 | MAPT (0.51) | GALR3MAPTTHRBALDH1A1GAA | |
| SCHEMBL7276577 | 0.83 | PDE3B (0.51) | GALR3MAPTTHRBALDH1A1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339208-B1 | 6-Oxopyridazine derivatives, process for their preparation and medicaments containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-4968683-A | INOTROPIC, CARDIOTONIC | HEUMANN PHARMA GMBH & CO. (DE) | 1990-11-06 | — | — | US | disclosed |