Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ODC1 | P11926 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890686 | 0.82 | KDM4E (0.59) | PDE4DKDM4ECASP1CASP7CA12 | |
| SCHEMBL5723204 | 0.81 | ALDH1A1 (0.35) | PDE4DKDM4ECASP1CASP7PTPN1 | |
| SCHEMBL16844642 | 0.80 | PTPN1 (0.43) | PDE4DKDM4ECASP1CASP7PTPN1 | |
| SCHEMBL5723068 | 0.80 | ALDH1A1 (0.35) | PDE4DKDM4ECASP1CASP7PTPN1 | |
| SCHEMBL16694463 | 0.77 | PTPN1 (0.65) | KDM4EPTPN1CA12CA1CA7 | |
| SCHEMBL31591499 | 0.77 | PTPN1 (0.65) | KDM4EPTPN1CA12CA1CA7 | |
| SCHEMBL5723520 | 0.75 | KDM4E (0.63) | PDE4DKDM4ECASP1CASP7CA12 | |
| SCHEMBL13422488 | 0.73 | PTPN1 (0.43) | PDE4DKDM4ECASP1CASP7PTPN1 | |
| SCHEMBL6607683 | 0.73 | ALDH1A1 (0.43) | KDM4ECASP1CASP7ALDH1A1LMNA | |
| SCHEMBL7308953 | 0.72 | KDM4E (0.38) | PDE4DKDM4ECASP1CASP7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819689-A1 | 5-substituted (2H) chromenes | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1998-01-21 | — | — | EP | disclosed |