Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659538 | 0.81 | TLR8 (0.42) | CYP1A2CYP2C9CYP2C19CD44 | |
| SCHEMBL4710713 | 0.79 | HTR2A (0.51) | SIGMAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL4763408 | 0.79 | BID (0.47) | — | |
| SCHEMBL7298930 | 0.78 | HTR1A (0.59) | HTR2AHTR1AHTR2BCYP2C9CYP2C19 | |
| SCHEMBL9163528 | 0.78 | BID (0.50) | — | |
| SCHEMBL9168071 | 0.78 | BID (0.50) | — | |
| SCHEMBL8088586 | 0.78 | BID (0.50) | — | |
| SCHEMBL9166810 | 0.78 | BID (0.50) | — | |
| SCHEMBL28748793 | 0.78 | BID (0.50) | — | |
| SCHEMBL10526794 | 0.78 | BID (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304789-B1 | BENZIMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-4925854-A | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0304789-A2 | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-01 | — | — | EP | disclosed |