Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 14/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | MLNR | O43193 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.66 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293461 | 0.88 | CACNA1B (0.58) | CACNA1BADORA3CACNA1CMEN1MLNR | |
| SCHEMBL9401939 | 0.86 | CACNA1F (0.66) | ADORA3CACNA1CMEN1KMT2APDE1C | |
| SCHEMBL9401841 | 0.86 | CACNA1B (0.56) | CACNA1BADORA3CACNA1CMEN1MLNR | |
| SCHEMBL9401782 | 0.86 | CACNA1B (0.56) | CACNA1BADORA3CACNA1CMEN1MLNR | |
| SCHEMBL9401969 | 0.86 | CACNA1B (0.56) | CACNA1BADORA3CACNA1CMEN1MLNR | |
| SCHEMBL7298605 | 0.85 | CACNA1B (1.00) | CACNA1BADORA3CACNA1CMEN1MLNR | |
| SCHEMBL7298610 | 0.85 | CACNA1B (1.00) | CACNA1BADORA3CACNA1CMEN1MLNR | |
| SCHEMBL10739973 | 0.85 | CACNA1B (1.00) | CACNA1BADORA3CACNA1CMEN1MLNR | |
| SCHEMBL10739981 | 0.85 | CACNA1B (1.00) | CACNA1BADORA3CACNA1CMEN1MLNR | |
| Hydrochloric Acid SCHEMBL7300133 | 0.84 | CACNA1B (0.98) | CACNA1BADORA3CACNA1CMEN1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320984-A2 | 1,4-Dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1989-06-21 | — | — | EP | disclosed |