Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 10/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401841 | 1.00 | CACNA1B (0.56) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL9401782 | 1.00 | CACNA1B (0.56) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL9401773 | 0.94 | CACNA1B (0.56) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL9401783 | 0.94 | CACNA1B (0.56) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL7290012 | 0.90 | CACNA1B (0.72) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL9401816 | 0.90 | CACNA1B (0.72) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL7290001 | 0.90 | CACNA1B (0.72) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL9401644 | 0.90 | CACNA1B (0.72) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL9401775 | 0.89 | CACNA1B (0.51) | CACNA1BADORA3CACNA1CMEN1KMT2A | |
| SCHEMBL9401787 | 0.89 | CACNA1B (0.51) | CACNA1BADORA3CACNA1CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |