Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | FHIT | P49789 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617595 | 0.86 | MAOB (0.50) | MAOBALDH1A1PKMMAPK1HSD17B10 | |
| SCHEMBL7291668 | 0.86 | ALDH1A1 (0.62) | MAOBALDH1A1PKMMAPK1HSD17B10 | |
| SCHEMBL5618385 | 0.79 | ALDH1A1 (0.54) | MAOBALDH1A1PKMMAPK1HSD17B10 | |
| SCHEMBL7302123 | 0.78 | MAOB (0.77) | MAOBACHEMAOA | |
| SCHEMBL7302247 | 0.76 | MAOB (0.45) | MAOBALDH1A1PKMMAPK1HSD17B10 | |
| SCHEMBL7293561 | 0.76 | KDM4E (0.53) | MAOBALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL7291407 | 0.71 | MAOB (0.64) | MAOBALDH1A1HSD17B10ACHEMAOA | |
| SCHEMBL7303132 | 0.71 | MAOB (0.43) | MAOBALDH1A1PKMMAPK1HSD17B10 | |
| SCHEMBL7302034 | 0.71 | MAOB (0.52) | MAOBALDH1A1RAB9ASMN1; SMN2ALDH2 | |
| SCHEMBL7293827 | 0.70 | MAOB (0.65) | MAOBALDH1A1MAPK1HSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363796-B1 | HETEROCYCLICALLY SUBSTITUTED ALKOXYCOUMARINES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5227392-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5073563-A | Enzyme inhibitors, CNS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |
| EP-0363796-A1 | Heterocyclically substituted alkoxycoumarines, method for their preparation and therapeutical agents containing same | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |