Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300476 | 1.00 | TBXAS1 (0.63) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| SCHEMBL7290691 | 0.88 | TBXAS1 (0.66) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| SCHEMBL7290697 | 0.88 | TBXAS1 (0.66) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| SCHEMBL9401668 | 0.88 | TBXAS1 (0.66) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| SCHEMBL15014112 | 0.86 | TBXAS1 (0.63) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| Hydrochloric Acid SCHEMBL10662048 | 0.84 | TBXAS1 (0.66) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| Hydrochloric Acid SCHEMBL10662064 | 0.84 | TBXAS1 (0.66) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| SCHEMBL10663227 | 0.83 | TBXAS1 (0.54) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| SCHEMBL10663209 | 0.83 | TBXAS1 (0.54) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 | |
| SCHEMBL10663127 | 0.83 | TBXAS1 (0.56) | TBXAS1CYP1A2CYP3A4CYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320984-A2 | 1,4-Dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1989-06-21 | — | — | EP | disclosed |