Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294073 | 0.90 | HTT (0.81) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL5376613 | 0.87 | HTT (0.77) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29961312 | 0.86 | HTT (0.82) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL5648998 | 0.85 | HTT (0.80) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6396133 | 0.85 | KMT2A (0.85) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7301496 | 0.84 | HTT (0.73) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7301422 | 0.84 | HTT (0.73) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11764394 | 0.84 | HTT (0.72) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7304335 | 0.84 | HTT (0.72) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7301679 | 0.83 | HTT (0.71) | HTTHPGDSMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |