Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | NPC1 | O15118 | 7/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189491 | 0.89 | HCAR3 (0.65) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL7301422 | 0.87 | HTT (0.73) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL7294073 | 0.87 | HTT (0.81) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL7302107 | 0.86 | NPC1 (0.69) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL7301679 | 0.86 | HTT (0.71) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL7301504 | 0.86 | HTT (0.71) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL5225002 | 0.85 | HTT (0.70) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL7300516 | 0.84 | HTT (1.00) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL5376613 | 0.84 | HTT (0.77) | HTTHPGDRAB9ANPC1MAPK1 | |
| SCHEMBL7245174 | 0.84 | NPC1 (0.76) | HTTRAB9ANPC1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |