SCHEMBL7300558

SCHEMBL7300558

CCCc1c[c]ccc1CC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9798034 0.91 PRKCI (0.32) PRKCI
SCHEMBL1404399 0.91
SCHEMBL58401 0.86 GABRA1 (0.33)
SCHEMBL27460611 0.84 GABRA1 (0.32)
SCHEMBL21268376 0.83 TYR (0.36)
SCHEMBL10458945 0.80 TAAR1 (0.31)
SCHEMBL4502800 0.78 TAAR1 (0.30)
SCHEMBL27274084 0.78
SCHEMBL2636670 0.78 GABRA1 (0.33)
SCHEMBL28321627 0.78 GABRA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019179774-A1 POLYMER COMPOSITION COMPRISING DIACETAL DERIVATIVES CLARIANT INTERNATIONAL LTD (CH) 2019-09-26 WO disclosed
WO-2019179773-A1 DIACETAL DERIVATIVES AND THEIR USE AS CLARIFIER CLARIANT INTERNATIONAL LTD (CH) 2019-09-26 WO disclosed
EP-3543244-A1 DIACETAL DERIVATIVES AND THEIR USE AS CLARIFIER Clariant International Ltd (CH) 2019-09-25 EP disclosed
EP-3543286-A1 POLYMER COMPOSITION COMPRISING DIACETAL DERIVATIVES Clariant International Ltd (CH) 2019-09-25 EP disclosed
EP-0835257-B1 INTERMEDIATES AND PROCESS FOR THE MANUFACTURE OF CAMPTOTHECIN DERIVATIVES (CPT-11) AND RELATED COMPOUNDS UPJOHN CO (US) 2002-09-25 EP disclosed
US-6444820-B1 ANTICARCINOGENIC AGENTS HENEGAR KEVIN E (US) 2002-09-03 US disclosed
US-6235907-B1 Intermediates useful in making mappicine and related compounds PHARMACIA & UPJOHN COMPANY 2001-05-22 US disclosed
US-6121451-A Intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds PHARMACIA & UPJOHN COMPANY (US) 2000-09-19 US disclosed
US-6060600-A TREATMENT OF AIDS AND OTHER DISEASES CAUSED BY RETROVIRUSES PHARMACIA & UPJOHN COMPANY (US) 2000-05-09 US disclosed
US-5977169-A FOR TREATMENT OF A PERSON WITH AIDS OR AIDS RELATED DISEASES PHARMACIA & UPJOHN COMPANY 1999-11-02 US disclosed
US-4029693-A HYPOTENSIVES, ANTISECRETORY, ANTIFERTILITY THE UPJOHN COMPANY (US) 1977-06-14 US disclosed
US-4028419-A PROSTAGLANDINS THE UPJOIN COMPANY (US) 1977-06-07 US disclosed
US-4028350-A ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1977-06-07 US disclosed
US-4026909-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1977-05-31 US disclosed
US-4018803-A 13,14-Didehydro-PG3 compounds THE UPJOHN COMPANY (US) 1977-04-19 US disclosed
US-4016184-A PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1977-04-05 US disclosed
US-4013695-A PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL THE UPJOHN COMPANY (US) 1977-03-22 US disclosed
US-4001300-A ANTIULCER, DECONGESTANT, LABOR INDUCER, WOUND HEALER THE UPJOHN COMPANY (US) 1977-01-04 US disclosed
US-3974146-A Cyanolpoxy intermediates for prostaglandins and process for preparing same THE UPJOHN COMPANY (US) 1976-08-10 US disclosed
US-3931279-A 5-Oxa prostaglandin F2.sub.α analogs THE UPJOHN COMPANY (US) 1976-01-06 US disclosed