Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719742 | 0.85 | NPC1 (0.74) | THRBSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL7293743 | 0.85 | KCNK3 (0.86) | KCNK3HDAC3HDAC6HDAC8KCNK9 | |
| SCHEMBL15149881 | 0.85 | MEN1 (0.49) | KCNK3HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL2348653 | 0.85 | SIRT1 (0.57) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL7291713 | 0.84 | NPC1 (0.79) | HDAC3HDAC6HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL1687867 | 0.84 | NPC1 (0.79) | HDAC3HDAC6HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL7293746 | 0.84 | NPC1 (0.79) | HDAC3HDAC6HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL7303163 | 0.83 | HDAC3 (0.86) | HDAC3HDAC6HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL7295360 | 0.83 | NR1H4 (0.60) | KCNK3HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL16678174 | 0.83 | HDAC3 (0.73) | HDAC3HDAC6HDAC8HDAC11KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |