Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.69 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.69 |
| ▸ | GABRP | O00591 | 4/20 | 0.69 |
| ▸ | GABRD | O14764 | 4/20 | 0.69 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.69 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.69 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.69 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.69 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.69 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.69 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.69 |
| ▸ | GABRE | P78334 | 4/20 | 0.69 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.69 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.69 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.69 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.69 |
| ▸ | G6PD | P11413 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12178194 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL13012758 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL4557360 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL18610325 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL22451788 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL23872369 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL598324 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL10308278 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL3049001 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL598323 | 1.00 | GABRA1 (0.69) | GABRA1GABRB2GABRPGABRDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941925-A1 | PROCESS FOR PREPARING HIGH PURITIY ALLOPREGNANOLONE AND INTERMEDIATES THEREOF | Crystal Pharma, S.A.U. (ES) | 2022-01-26 | — | — | EP | claimed |
| WO-2020187965-A1 | PROCESS FOR PREPARING HIGH PURITIY ALLOPREGNANOLONE AND INTERMEDIATES THEREOF | BIONICE, S.L.U. (ES) | 2020-09-24 | — | — | WO | claimed |
| EP-3941925-A1 | PROCESS FOR PREPARING HIGH PURITIY ALLOPREGNANOLONE AND INTERMEDIATES THEREOF | Crystal Pharma, S.A.U. (ES) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020187965-A1 | PROCESS FOR PREPARING HIGH PURITIY ALLOPREGNANOLONE AND INTERMEDIATES THEREOF | BIONICE, S.L.U. (ES) | 2020-09-24 | — | — | WO | disclosed |
| EP-0583579-B1 | New 17-hydroxyiminomethyl-5beta, 14beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same | SIGMA TAU IND FARMACEUTI (IT) | 1997-12-03 | — | — | EP | disclosed |
| US-5444055-A | Treatment of heart failure, hypertension | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1995-08-22 | — | — | US | disclosed |
| EP-0583579-A2 | New 17-hydroxyiminomethyl-5beta, 14beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1994-02-23 | — | — | EP | disclosed |