Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9036671 | 0.99 | SETD7 (0.57) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| SCHEMBL9034546 | 0.89 | SETD7 (0.64) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7212638 | 0.88 | SETD7 (0.62) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| SCHEMBL9034968 | 0.86 | SETD7 (0.61) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7218968 | 0.85 | SETD7 (0.59) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| SCHEMBL9591452 | 0.85 | SETD7 (0.44) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| SCHEMBL9035029 | 0.81 | SETD7 (0.67) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| SCHEMBL9036131 | 0.80 | SETD7 (0.70) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7212855 | 0.80 | SETD7 (0.66) | SETD7ADRA1DADRA1AKCNH2SLC6A4 | |
| SCHEMBL7435858 | 0.80 | SETD7 (0.62) | SETD7ADRA1DADRA1AKCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |