Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7218758 | 0.99 | SETD7 (0.60) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7217886 | 0.95 | SETD7 (0.62) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| SCHEMBL9035029 | 0.90 | SETD7 (0.67) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7212855 | 0.88 | SETD7 (0.66) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7217676 | 0.86 | SIGMAR1 (0.57) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| SCHEMBL9036131 | 0.86 | SETD7 (0.70) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7212357 | 0.85 | SETD7 (0.68) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| SCHEMBL9034527 | 0.84 | SETD7 (0.61) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7218867 | 0.84 | SETD7 (0.60) | SETD7SIGMAR1HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7218782 | 0.84 | SETD7 (0.70) | SETD7SIGMAR1HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| US-5250681-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |