Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 16/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723126 | 0.77 | PDE4A (0.39) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL5722950 | 0.77 | PDE4A (0.39) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL8326536 | 0.74 | MAPT (0.45) | PDE4B | |
| SCHEMBL7300353 | 0.74 | MAPT (0.45) | PDE4B | |
| SCHEMBL5722871 | 0.73 | PDE4B (0.40) | HIF1APDE4APDE4BPDE4DPDE4C | |
| SCHEMBL5722773 | 0.72 | PDE4B (0.36) | HIF1APDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7303717 | 0.71 | SMN1; SMN2 (0.35) | HIF1A | |
| SCHEMBL5722826 | 0.70 | KDM4E (0.44) | HIF1APDE4D | |
| SCHEMBL5723023 | 0.69 | KDM4E (0.43) | HIF1APDE4D | |
| SCHEMBL5722916 | 0.69 | PDE4B (0.38) | PDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819689-A1 | 5-substituted (2H) chromenes | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1998-01-21 | — | — | EP | disclosed |