Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KLK1 | P06870 | 4/20 | 0.51 |
| ▸ | PLAU | P00749 | 7/20 | 0.51 |
| ▸ | F2 | P00734 | 6/20 | 0.51 |
| ▸ | PLAT | P00750 | 6/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 6/20 | 0.48 |
| ▸ | KLK8 | O60259 | 5/20 | 0.48 |
| ▸ | KLK4 | Q9Y5K2 | 5/20 | 0.48 |
| ▸ | F10 | P00742 | 4/20 | 0.48 |
| ▸ | KLK2 | P20151 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300806 | 0.84 | ELANE (0.51) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL9155282 | 0.78 | CA12 (0.56) | ELANEKLK1CA12CA1CA2 | |
| SCHEMBL28537302 | 0.77 | CA12 (0.55) | ELANETP53PLAUF2PLAT | |
| SCHEMBL9155285 | 0.77 | CA12 (0.55) | ELANECA12CA1CA2CA9 | |
| SCHEMBL13485419 | 0.76 | ELANE (0.57) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL9462241 | 0.76 | CA12 (0.61) | ELANETP53CA12CA1CA2 | |
| SCHEMBL13537615 | 0.74 | ELANE (0.55) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL8519322 | 0.74 | TSHR (0.53) | ELANE | |
| SCHEMBL119805 | 0.73 | CA12 (0.67) | CA12CA1CA2CA9 | |
| SCHEMBL13875657 | 0.72 | ALDH1A1 (0.47) | ELANETP53KLK1PLAUF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0473936-A1 | Renin Inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |