Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 10/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 10/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 10/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 10/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 10/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303392 | 0.86 | KLK5 (0.46) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10444524 | 0.84 | PSEN1 (0.46) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7293840 | 0.84 | KLK5 (0.46) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7300241 | 0.82 | PSEN1 (0.55) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7299761 | 0.77 | PSEN1 (0.56) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7324970 | 0.77 | PSEN1 (0.41) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2059396 | 0.76 | KLK5 (0.58) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7298687 | 0.76 | PTPN1 (0.45) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7295474 | 0.75 | KLK5 (0.41) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7293225 | 0.74 | PSEN1 (0.52) | KLK5PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337714-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1989-10-18 | — | — | EP | disclosed |