Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302675 | 0.78 | F2 (0.75) | F2 | |
| Acetic Acid SCHEMBL8919662 | 0.77 | F2 (0.72) | F2 | |
| Acetic Acid SCHEMBL8579129 | 0.74 | F2 (0.52) | F2MAPTF10ALDH1A1 | |
| SCHEMBL8919686 | 0.74 | F2 (0.54) | F2MAPTF10ALDH1A1 | |
| SCHEMBL7290829 | 0.68 | F2 (0.78) | F2 | |
| SCHEMBL7290808 | 0.68 | F2 (0.78) | F2 | |
| SCHEMBL7291503 | 0.68 | F2 (0.51) | F2 | |
| SCHEMBL8926218 | 0.67 | F2 (0.42) | F2F10 | |
| SCHEMBL8927498 | 0.66 | F2 (0.42) | F2F10 | |
| SCHEMBL7302895 | 0.66 | F2 (0.58) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468231-B1 | Guanidins | HOFFMANN LA ROCHE (CH) | 1994-09-21 | — | — | EP | disclosed |