Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.54 |
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | PLG | P00747 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.39 |
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | IL2RA | P01589 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302675 | 0.84 | F2 (0.75) | F2 | |
| Acetic Acid SCHEMBL8919662 | 0.84 | F2 (0.72) | F2 | |
| SCHEMBL8918410 | 0.81 | F2 (0.53) | F2ST14PLAUIL2RAALB | |
| Acetic Acid SCHEMBL8579129 | 0.80 | F2 (0.52) | F2F10PLGALDH1A1MAPT | |
| SCHEMBL7290829 | 0.74 | F2 (0.78) | F2 | |
| SCHEMBL7290808 | 0.74 | F2 (0.78) | F2 | |
| SCHEMBL7300871 | 0.74 | F2 (0.47) | F2F10ALDH1A1MAPT | |
| Sulfurous Acid SCHEMBL8922012 | 0.72 | F2 (0.74) | F2 | |
| SCHEMBL8578919 | 0.72 | F2 (0.70) | F2 | |
| SCHEMBL8918553 | 0.71 | F2 (0.71) | F2IL2RAALBIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595999-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1997-01-21 | — | — | US | disclosed |
| US-5583133-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-12-10 | — | — | US | disclosed |
| US-5532232-A | INHIBIT THROMBIN INDUCED PLATELET AGGREGATION; FIBRINOGEN ANTICOAGULANTS IN BLOOD | HOFFMANN-LA ROCHE INC. (US) | 1996-07-02 | — | — | US | disclosed |
| US-5393760-A | Cardiovascular disorders, antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| US-5260307-A | Inhibit thrombin-induced platlet aggregation and clotting of fibrogen in plasma | HOFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |