Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 15/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476280 | 0.96 | FKBP1A (0.58) | FKBP1AACE | |
| SCHEMBL11021498 | 0.96 | FKBP1A (0.54) | FKBP1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL6793612 | 0.94 | FKBP1A (0.62) | FKBP1AACE | |
| SCHEMBL6793620 | 0.94 | FKBP1A (0.62) | FKBP1AACE | |
| SCHEMBL6787342 | 0.94 | FKBP1A (0.62) | FKBP1AACE | |
| SCHEMBL6786218 | 0.94 | FKBP1A (0.62) | FKBP1AACE | |
| SCHEMBL6786208 | 0.94 | FKBP1A (0.62) | FKBP1AACE | |
| SCHEMBL9097059 | 0.93 | FKBP1A (0.61) | FKBP1AACE | |
| SCHEMBL6784238 | 0.93 | FKBP1A (0.61) | FKBP1AACE | |
| SCHEMBL6784258 | 0.93 | FKBP1A (0.61) | FKBP1AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506256-A | PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |