Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | ACACA | Q13085 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26027547 | 0.84 | ACACB (0.61) | ACACBACACAAOC3S1PR1S1PR3 | |
| SCHEMBL7294501 | 0.84 | ACACB (0.69) | ACACBACACAAOC3S1PR1S1PR3 | |
| SCHEMBL7295310 | 0.84 | ACACB (0.52) | ACACBACACAAOC3S1PR1S1PR3 | |
| SCHEMBL7295162 | 0.83 | NR1H4 (0.59) | AOC3S1PR1S1PR3MCHR1ACHE | |
| SCHEMBL7302028 | 0.79 | ACACB (0.70) | ACACBACACAS1PR1S1PR3RAB9A | |
| SCHEMBL29823336 | 0.78 | SMN1; SMN2 (0.70) | S1PR1S1PR3LMNANFKB1RAB9A | |
| SCHEMBL26022112 | 0.78 | AOC3 (0.52) | ACACBACACAAOC3S1PR1S1PR3 | |
| SCHEMBL9522122 | 0.76 | AOC3 (0.50) | ACACBACACAAOC3S1PR1S1PR3 | |
| SCHEMBL9706125 | 0.75 | EBP (0.72) | EBPSIGMAR1ESR1MCHR1HRH3 | |
| SCHEMBL3505092 | 0.75 | L3MBTL1 (0.55) | ACACBACACAAOC3S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |