SCHEMBL7301155

SCHEMBL7301155

O=C[C@H]1NCC(=S)C1C(=O)[C@H]1NCC(=S)C1C(=O)CC1=Cc2ccccc2C1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.35
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9047815 0.89 PREP (0.34) PREPACHE
SCHEMBL7295503 0.88 PREP (0.36) PREPACHE
SCHEMBL7292572 0.85 PREP (0.38) PREPACHE
SCHEMBL7294230 0.82 PREP (0.33) PREPACHE
SCHEMBL7292862 0.80 PREP (0.47) PREPACHE
SCHEMBL9049370 0.80 ACHE (0.31) ACHE
SCHEMBL7295142 0.80 PREP (0.34) PREPACHE
SCHEMBL7291285 0.80
SCHEMBL7301278 0.80 PREP (0.53) PREPACHE
SCHEMBL7303125 0.80 PREP (0.35) PREPACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed