Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.66 |
| ▸ | RXRB | P28702 | 1/20 | 0.66 |
| ▸ | RXRG | P48443 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 5/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16697339 | 0.84 | NR4A2 (0.60) | MAOBMAOADHFRF2NR4A2 | |
| SCHEMBL16697343 | 0.84 | NR4A2 (0.60) | MAOBMAOADHFRF2NR4A2 | |
| SCHEMBL7301072 | 0.83 | PARP10 (0.66) | MAOBMAOAF2NR4A2 | |
| SCHEMBL3624161 | 0.80 | MAOB (0.73) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL29784197 | 0.79 | RXRA (1.00) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL6522344 | 0.79 | RXRA (1.00) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL1680762 | 0.79 | MAOB (1.00) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL9627120 | 0.79 | MAOB (0.76) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL8378348 | 0.78 | F2 (0.51) | RXRARXRBRXRGMAOBF2 | |
| SCHEMBL8378347 | 0.78 | F2 (0.51) | RXRARXRBRXRGMAOBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0504574-A1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-23 | — | — | EP | claimed |
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5356916-A | Treating Parkinson*s disease | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0504574-A1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-23 | — | — | EP | disclosed |