Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.86 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.86 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305310 | 0.95 | ITGB3 (0.78) | ITGB3ITGA2BPLAUNPC1CASP3 | |
| SCHEMBL7299540 | 0.93 | ITGB3 (1.00) | ITGB3ITGA2BPLAU | |
| Hydrochloric Acid SCHEMBL7315319 | 0.92 | ITGB3 (0.98) | ITGB3ITGA2B | |
| SCHEMBL7309708 | 0.89 | ITGB3 (0.88) | ITGB3ITGA2BPLAUNPC1CASP3 | |
| SCHEMBL7299150 | 0.88 | ITGB3 (0.67) | ITGB3ITGA2BPLAUHDAC1NPC1 | |
| SCHEMBL7309322 | 0.87 | ITGB3 (0.66) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7305871 | 0.87 | ITGB3 (0.78) | ITGB3ITGA2BPLAUHDAC1NPC1 | |
| SCHEMBL7300011 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7314088 | 0.84 | ITGB3 (0.83) | ITGB3ITGA2B | |
| SCHEMBL7393898 | 0.84 | ITGB3 (0.85) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |