Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 16/20 | 0.57 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297854 | 1.00 | PREP (0.57) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL7295937 | 1.00 | PREP (0.57) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL7296683 | 0.94 | PREP (0.52) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL7305071 | 0.91 | PREP (0.51) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL7296356 | 0.88 | PREP (0.54) | PREP | |
| SCHEMBL7294240 | 0.88 | PREP (0.54) | PREP | |
| SCHEMBL7302246 | 0.88 | PREP (0.54) | PREP | |
| SCHEMBL7294732 | 0.87 | DPP4 (0.44) | PREPDPP4DPP8DPP9 | |
| SCHEMBL7300887 | 0.84 | PREP (0.46) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL7294362 | 0.84 | PREP (0.46) | PREPDPP4FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017929-A | Cholinesterase activator | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0754454-A1 | CHOLINESTERASE ACTIVATOR | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |