SCHEMBL7300887

SCHEMBL7300887

O=C(CCCC1Cc2ccccc2C1)C1C(=S)CN[C@@H]1C(=O)N1CCSC1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PREP P48147 9/20 0.46
DPP4 P27487 10/20 0.40
FAP Q12884 1/20 0.40
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7296683 0.89 PREP (0.52) PREPDPP4FAPDPP8DPP9
SCHEMBL7305071 0.88 PREP (0.51) PREPDPP4FAPDPP8DPP9
SCHEMBL7291297 0.87 PREP (0.49) PREPDPP4FAP
SCHEMBL7297854 0.84 PREP (0.57) PREPDPP4FAPDPP8DPP9
SCHEMBL7301347 0.84 PREP (0.57) PREPDPP4FAPDPP8DPP9
SCHEMBL7295937 0.84 PREP (0.57) PREPDPP4FAPDPP8DPP9
SCHEMBL7300891 0.83 PREP (0.48) PREPDPP4FAPDPP8DPP9
SCHEMBL7291631 0.83 PREP (0.35) PREP
SCHEMBL7303628 0.82 DPP4 (0.38) PREPDPP4FAPDPP8DPP9
SCHEMBL9791386 0.81 PREP (0.47) PREPDPP4FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed