Phenol

Phenol

SCHEMBL730141

COC(=O)OC.Oc1ccccc1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.55
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
CA9 Q16790 4/20 0.55
CA14 Q9ULX7 4/20 0.55
CA3 P07451 2/20 0.55
CA4 P22748 2/20 0.55
GLA P06280 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
TSHR P16473 4/20 0.50
KMT2A Q03164 3/20 0.50
HSD17B10 Q99714 2/20 0.48
KDM4E B2RXH2 1/20 0.48
HPGD P15428 1/20 0.48
CA7 P43166 3/20 0.48
CYP3A4 P08684 2/20 0.46
ALOX5 P09917 1/20 0.46
KCNN4 O15554 1/20 0.45
LMNA P02545 1/20 0.45
MAOA P21397 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL14935630 0.93 CA12 (0.48) CA12CA1CA2CA9CA14
Phenol SCHEMBL25374179 0.87 CA12 (0.58) CA12CA1CA2CA9CA14
Phenol SCHEMBL18603299 0.87 CA12 (0.58) CA12CA1CA2CA9CA14
Hydroquinone SCHEMBL29193635 0.87 CA12 (0.61) CA12CA1CA2CA9CA14
Phenol SCHEMBL11062329 0.85 CA12 (0.55) CA12CA1CA2CA9CA14
Phenol SCHEMBL28245188 0.85 CA12 (0.55) CA12CA1CA2CA9CA14
Phenol SCHEMBL28467088 0.83 CA12 (0.52) CA12CA1CA2CA9CA14
Phenol SCHEMBL27975587 0.83 CA12 (0.52) CA12CA1CA2CA9CA14
Biphenyl SCHEMBL27492413 0.82 TSHR (0.52) TSHRKMT2AHSD17B10KDM4EHPGD
Phenol SCHEMBL547014 0.81 CA2 (0.73) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117696038-A Modified magnesium-aluminum hydrotalcite catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2024-03-15 CN disclosed
CN-110577633-B Pretreatment system and method for polycarbonate production raw materials 利华益维远化学股份有限公司 2023-12-19 CN disclosed
WO-2023068288-A1 METHOD FOR PRODUCING DIPHENYL CARBONATE 旭化成株式会社 2023-04-27 WO disclosed
CN-110183949-A A kind of preparation method of resin base hydrophobic silica corrosion-inhibiting coating 郭英杰 2019-08-30 CN disclosed
CN-101331107-B Industrial process for production of high-purity diaryl carbonates ASAHI KASEI CHEMICALS CORP (JP) 2012-06-27 CN disclosed
CN-101321805-B Industrial production process for high-quality aromatic polycarbonate ASAHI KASEI CHEMICALS CORP (JP) 2012-03-28 CN disclosed
US-8138367-B2 ester interchange, reactive distillation, catalytic aromatization in presence of titanium tetraphenoxide to form diphenyl carbonate, can be produced continuously with a high yield ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-03-20 US disclosed
CN-101331168-B Industrial production method for aromatic polycarbonate ASAHI CHEMICAL IND (JP) 2011-08-31 CN disclosed
US-7884251-B2 from a large amount of a low boiling point reaction mixture containing by-produced alcohols when mass-producing an aromatic carbonate on an industrial scale by subjecting a dialkyl carbonate and an aromatic monohydroxy compound to transesterification reaction in a reactive distillation column ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-02-08 US disclosed
US-7777067-B2 Industrial process for production of an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-08-17 US disclosed
US-6600061-B1 Method for making aromatic carbonates. In this method, an aryl alcohol is reacted with a dialkyl carbonate in a reactor (e.g., a distillation column) to produce an arylalkyl carbonate and diaryl carbonate. The total yield is 40% GENERAL ELECTRIC COMPANY 2003-07-29 US disclosed
US-6596895-B2 Diphenyl carbonate is made by reacting an aryl alcohol with a dialkyl carbonate to produce aryl alkylcarbonate and diaryl carbonate and reacting the diphenyl carbonate with a dihydric phenol to produce an aromatic polycarbonate GENERAL ELECTRIC COMPANY 2003-07-22 US disclosed
US-6596894-B2 Feeding the top section of a distillation column an aryl alcohol and a titanium alkyl or aryl oxide catalyst and the bottom that has a temperature of 220-240 degrees C a dialkyl carbonate GENERAL ELECTRIC COMPANY 2003-07-22 US disclosed
US-20020156312-A1 Feeding the top section of a distillation column an aryl alcohol and a titanium alkyl or aryl oxide catalyst and the bottom that has a temperature of 220-240 degrees C a dialkyl carbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-10-24 US disclosed
US-20020107355-A1 Method for the continuous production of aromatic carbonates SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-08-08 US disclosed
EP-0780361-B1 Manufacturing method for aromatic carbonates GEN ELECTRIC (US) 2000-09-06 EP disclosed
EP-0785184-B1 Continuous process for the preparation of phenyl methyl carbonate ENICHEM SPA (IT) 2000-04-05 EP disclosed
US-5705673-A REACTION OF PHENOL AND DIMETHYL CARBONATE IN THE PRESENCE OF ESTER EXCHANGE CATALYSTS ENICHEM S.P.A. (IT) 1998-01-06 US disclosed
EP-0785184-A1 Continuous process for the preparation of phenyl methyl carbonate ENICHEM S.p.A. (IT) 1997-07-23 EP disclosed
EP-0780361-A1 Manufacturing method for aromatic carbonates GENERAL ELECTRIC COMPANY (US) 1997-06-25 EP disclosed