Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.78 |
| ▸ | TP53 | P04637 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696412 | 0.93 | NR1H4 (0.77) | SMN1; SMN2TP53MAPTNR1H4ALDH1A1 | |
| SCHEMBL27775817 | 0.89 | KMT2A (0.64) | SMN1; SMN2TP53MAPTNR1H4MEN1 | |
| SCHEMBL2814444 | 0.88 | KMT2A (0.62) | SMN1; SMN2TP53MAPTNR1H4MEN1 | |
| SCHEMBL2815596 | 0.85 | KMT2A (0.60) | SMN1; SMN2TP53MAPTNR1H4MEN1 | |
| SCHEMBL2816013 | 0.85 | MEN1 (0.60) | SMN1; SMN2TP53MAPTNR1H4MEN1 | |
| SCHEMBL2816734 | 0.85 | MAPT (0.62) | SMN1; SMN2TP53MAPTNR1H4MEN1 | |
| SCHEMBL27775777 | 0.85 | MEN1 (0.60) | SMN1; SMN2TP53MAPTNR1H4MEN1 | |
| SCHEMBL2814428 | 0.85 | KMT2A (0.60) | SMN1; SMN2TP53MAPTNR1H4MEN1 | |
| SCHEMBL15480650 | 0.85 | MEN1 (0.70) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL2814413 | 0.84 | MEN1 (0.76) | SMN1; SMN2TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |