Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | PKM | P14618 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | NQO2 | P16083 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18407544 | 0.92 | NPC1 (0.78) | MEN1KMT2AALDH1A1PKMNPC1 | |
| SCHEMBL1436474 | 0.89 | SMPD1 (0.66) | MEN1KMT2AALDH1A1PKMHDAC8 | |
| Hydrochloric Acid SCHEMBL9638760 | 0.87 | SMPD1 (0.64) | MEN1KMT2AALDH1A1PKMHDAC8 | |
| SCHEMBL11162884 | 0.86 | PKM (0.82) | MEN1KMT2AALDH1A1PKMNPC1 | |
| SCHEMBL17664663 | 0.86 | MEN1 (0.72) | MEN1KMT2AALDH1A1PKMNPC1 | |
| SCHEMBL7301440 | 0.85 | SMN1; SMN2 (0.78) | MEN1KMT2AALDH1A1PKMNPC1 | |
| SCHEMBL13561145 | 0.85 | KMT2A (0.70) | MEN1KMT2AALDH1A1PKMNPC1 | |
| SCHEMBL4141962 | 0.84 | MEN1 (0.89) | MEN1KMT2AALDH1A1PKMNPC1 | |
| SCHEMBL5943717 | 0.84 | POLB (0.65) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4026426 | 0.84 | MEN1 (0.61) | MEN1KMT2AALDH1A1PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051716-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB | 2014-02-20 | — | — | US | disclosed |
| US-20140051716-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051716-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | MEN1 4342/4885KMT2A 223/4885ALDH1A1 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.